Lu-177 DOTATATE + Triapine in GEP-NETs

PHASE 1 Trial, Testing the Addition of an Anti-cancer Drug, Triapine, to the Usual Radiation-Based Treatment (Lutetium Lu-177 Dotatate) for Neuroendocrine Tumors 

DRUG/TREATMENT:  LUTATHERA (Lu-177) + Triapine

CLINICALTRIALS.GOV IDENTIFIER:  NCT04234568

PHASE: 1

STATUS: Active, not recruiting

SPONSOR: National Cancer Institute (NCI)

Dr. Aman Chauhan discusses LUTATHERA (Lu-177) + Triapine

DESCRIPTION:

This phase I trial studies the side effects and best dose of triapine when given together with lutetium Lu-177 dotatate in treating patients with neuroendocrine tumors. Triapine may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Radioactive drugs, such as lutetium Lu-177 dotatate, may carry radiation directly to tumor cells and not harm normal cells. Giving triapine and lutetium Lu-177 dotatate together may be a good way in treating patients with neuroendocrine tumors.

For more information on eligibility criteria, trial locations, study details, etc., go to ClinicalTrials.gov to view this trial here.

CONTACT/Principal Investigator:

Aman Chauhan, MD

EMAIL: axc3268@med.miami.edu